Determinants of Plasma Renin Activity
نویسندگان
چکیده
منابع مشابه
Determinants of Plasma Renin Activity
The plasma renin activity (PRA) is affected by a number of environmental factors. However, significant heritability has been shown for the activity. A hypothesis that a candidate regulatory single-nucleotide polymorphism, C-5312T, of human renin gene should have a significant effect on PRA was elucidated and updating of independent determinants of PRA was attempted. Cross sectional study.
متن کاملPlasma renin activity and plasma prorenin assays.
Sensitivity and accuracy are essential features of an assay of plasma renin activity (PRA) because the normal concentration of PRA is only 1 pmol/L, and subnormal concentrations have diagnostic relevance. Conditions for blood collection need to be standardized but the conditions are not difficult for outpatients. For routine diagnostic purposes blood should be collected from ambulatory (ideally...
متن کاملThe effect of aspirin therapy on the plasma renin activity in myocardial infarction
In this study, the changes of renin system activity and the effects of aspirin therapy on the plasma renin activity ( PRA) in myocardial infarction were investigated. Fifty nine patients with myocardial infarction were selected. By suppressed in the former group which was statistically significant ( p<0.01).
متن کاملMeasurement of renin activity in human plasma.
• Many methods for measurement of renin activity have been described since Tigerstedt and Bergman first made an extract of kidney and showed that when injected it raised blood pressure. Those methods which rely on the rise of blood pressure following such injections suffer from three main disadvantages. First, the magnitude of response to a given dose may vary and tachyphylaxis can be elicited....
متن کاملDirect renin assay and plasma renin activity assay compared.
substances produced an interference 5% compared with the serum diluted with drug cocktail diluent. The list of drugs tested appears in Supplement 1, which accompanies the online version of this Technical Brief at http:// www.clinchem.org/content/vol50/issue11/. Ion suppression was assessed as recommended by Annesley (12 ). Briefly, the response of calibrators injected into the mobile phase was ...
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ژورنال
عنوان ژورنال: Medicine
سال: 2014
ISSN: 0025-7974
DOI: 10.1097/md.0000000000000354